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Section 1. Active and Passive Immunization
ACTIVE IMMUNIZATION
Active Immunization of People Who Recently Received Immune Globulin
Live-virus vaccines may have diminished immunogenicity when given shortly before or during the several months after receipt of IG. In particular, IG administration has been demonstrated to inhibit the response to measles vaccine for a prolonged period. Inhibition of immune response to rubella vaccine also has been demonstrated. The appropriate suggested interval between IG administration and measles immunization will vary with the indication for, and dose of, IG and the specific product; suggested intervals are given in Table 3.33 (p 423). If IG must be given within 14 days after administration
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