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Section 1. Active and Passive Immunization
ACTIVE IMMUNIZATION
Minimum Ages and Minimum Intervals Between Vaccine Doses
Immunizations are recommended for members of the youngest age group at risk of experiencing the disease for whom efficacy, immunogenicity, and safety have been demonstrated. Most vaccines in the childhood and adolescent immunization schedule require 2 or more doses for stimulation of an adequate and persisting antibody response. Studies have demonstrated that the recommended age and interval between doses of the same antigen(s) provide optimal protection and efficacy. Table 1.7 shows the recommended minimum ages and intervals between immunizations for vaccines in the recommended childhood immunization schedule. Administering
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