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Section 3. Summaries of Infectious Diseases
CHLAMYDIAL INFECTIONS
Chlamydophila (formerly Chlamydia) pneumoniae
Clinical Manifestations
Etiology
Epidemiology
Diagnostic Tests
Treatment
Isolation of the Hospitalized Patient
Control Measures
CLINICAL MANIFESTATIONS: Patients may be asymptomatic or mildly
to moderately ill with a variety of respiratory tract diseases,
including pneumonia, acute bronchitis, prolonged cough, and
less commonly, pharyngitis, laryngitis, otitis media, and sinusitis.
In some patients, a sore throat precedes the onset of cough
by a week or more. Physical examination may reveal nonexudative
pharyngitis, pulmonary rales, and bronchospasm. Chest radiography
may reveal an infiltrate. Illness is prolonged, with cough persisting
2 to 6 weeks, and can have a biphasic course. In addition to
acute respiratory tract disease, some investigators have associated
C pneumoniae with atherosclerotic cardiovascular disease. Prospective,
randomized trials are underway to further explore this association.
ETIOLOGY: Chlamydophila pneumoniae is
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Related text in Red Book:
- Introduction
Red Book
2006: 735.
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This topic has been referenced by these articles:
- Ronchetti, R., Villa, M. P., Martella, S., La Grutta, S., Ronchetti, F., Luca Biscione, G., Pagani, J., Falasca, C., Guglielmi, F., Barreto, M.
(2002). Nasal Cellularity in 183 Unselected Schoolchildren Aged 9 to 11 Years. Pediatrics
110: 1137-1142
[Abstract]
[Full Version]
- Neumayr, L., Lennette, E., Kelly, D., Earles, A., Embury, S., Groncy, P., Grossi, M., Grover, R., McMahon, L., Swerdlow, P., Waldron, P., Vichinsky, E.
(2003). Mycoplasma Disease and Acute Chest Syndrome in Sickle Cell Disease. Pediatrics
112: 87-95
[Abstract]
[Full Version]
- Goyal, M., Miller, S. T., Hammerschlag, M. R., Gelling, M., Gaydos, C. A., Hardick, J., Wood, B. J., Reznik, T., Rao, S.P.
(2004). Is Chlamydia pneumoniae Infection Associated With Stroke in Children With Sickle Cell Disease?. Pediatrics
113: e318-e321
[Abstract]
[Full Version]
- Yamazaki, T., Murayama, K., Ito, A., Uehara, S., Sasaki, N.
(2005). Epidemiology of Community-Acquired Pneumonia in Children. Pediatrics
115: 517-517
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- Michelow, I. C., Olsen, K., Lozano, J., Rollins, N. K., Duffy, L. B., Ziegler, T., Kauppila, J., Leinonen, M., McCracken, G. H. Jr
(2004). Epidemiology and Clinical Characteristics of Community-Acquired Pneumonia in Hospitalized Children. Pediatrics
113: 701-707
[Abstract]
[Full Version]
- Christakis, D. A., Zimmerman, F. J., DiGiuseppe, D. L., McCarty, C. A.
(2004). Early Television Exposure and Subsequent Attentional Problems in Children. Pediatrics
113: 708-713
[Abstract]
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