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The following text is from an archived Red Book® edition and may not reflect current recommendations or information. To view the current edition, click here.

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Section 3. Summaries of Infectious Diseases

CHLAMYDIAL INFECTIONS

Chlamydophila (formerly Chlamydia) pneumoniae

Clinical Manifestations
Etiology
Epidemiology
Diagnostic Tests
Treatment
Isolation of the Hospitalized Patient
Control Measures

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CLINICAL MANIFESTATIONS: Patients may be asymptomatic or mildly to moderately ill with a variety of respiratory tract diseases, including pneumonia, acute bronchitis, prolonged cough, and less commonly, pharyngitis, laryngitis, otitis media, and sinusitis. In some patients, a sore throat precedes the onset of cough by a week or more. Physical examination may reveal nonexudative pharyngitis, pulmonary rales, and bronchospasm. Chest radiography may reveal an infiltrate. Illness is prolonged, with cough persisting 2 to 6 weeks, and can have a biphasic course. In addition to acute respiratory tract disease, some investigators have associated C pneumoniae with atherosclerotic cardiovascular disease. Prospective, randomized trials are underway to further explore this association.


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ETIOLOGY: Chlamydophila pneumoniae is . . . [Go to Full Text]


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