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Appendices

The following text is from an archived Red Book® edition and may not reflect current recommendations or information. To view the current edition, click here.

The first 300 words of the full text of this section appear below.

Section 3. Summaries of Infectious Diseases

Human Papillomaviruses

Clinical Manifestations
Etiology
Epidemiology
Diagnostic Tests
Treatment
Isolation of the Hospitalized Patient
Control Measures

CLINICAL MANIFESTATIONS: Most human papillomavirus (HPV) infections produce no lesions and are inapparent clinically. However, HPVs can produce benign epithelial proliferation (warts) of the skin and mucous membranes and are associated with anogenital dysplasias and cancers. Cutaneous nongenital warts include common skin warts, plantar warts, flat warts, thread-like (filiform) warts, and epidermodysplasia verruciformis. Warts also occur on the mucous membranes, including the anogenital, oral, nasal, and conjunctival areas and the respiratory tract, where respiratory papillomatosis occurs.

Common skin warts are dome-shaped with conical projections that give the surface a rough appearance. They usually are painless and multiple, occurring commonly on the hands and around or under the nails. When small dermal vessels become thrombosed, black dots appear in the warts. Plantar warts on the foot may be painful and are characterized by marked hyperkeratosis, sometimes with black dots.

Flat warts ("juvenile warts") commonly are found on the face and extremities of children and adolescents. They usually are small, multiple, and flat topped; seldom exhibit papillomatosis; and rarely cause pain. Filiform warts occur on the face and neck. Cutaneous warts are benign.

Anogenital warts, also called condylomata acuminata, are skin-colored warts with a cauliflower-like surface that range in size from a few millimeters to several centimeters. In males, these warts may be found on the penis, scrotum, or anal and perianal area. In females, these lesions may occur on the vulva or perianal areas and less commonly in the vagina or on the cervix. Anogenital warts often are multiple and attract attention because of their appearance. Warts usually are painless, although they may cause itching, burning, local pain, or bleeding.

Anogenital HPV infection may be associated with clinically . . . [Go to Full Text]


Related text in Red Book:

Sexually Transmitted Infections

Red Book 2006: 766-773. [Extract] [Full Version]  




This topic has been referenced by these articles:

  • Mmeje, O., Davis, M. M. (2006). Will Coverage for Child and Adolescent Immunizations Be Mandated for Insurance Plans in 2006? Lessons Learned From the Newborns' and Mothers' Health Protection Act of 1996. Pediatrics 118: 388-392 [Full Version]  
  • Giaquinto, C., Del Mistro, A., De Rossi, A., Bertorelle, R., Giacomet, V., Ruga, E., Minucci, D. (2000). Vulvar Carcinoma in a 12-Year-Old Girl With Vertically Acquired Human Immunodeficiency Virus Infection. Pediatrics 106: 57e-57 [Abstract] [Full Version]  
  • Stevens-Simon, C., Nelligan, D., Breese, P., Jenny, C., Douglas Jr., J. M. (2000). The Prevalence of Genital Human Papillomavirus Infections in Abused and Nonabused Preadolescent Girls. Pediatrics 106: 645-649 [Abstract] [Full Version]  
  • Godfrey, J. C., Vaughan, M. C., Williams, J. V. (2003). Successful Treatment of Bowenoid Papulosis in a 9-Year-Old Girl With Vertically Acquired Human Immunodeficiency Virus. Pediatrics 112: e73-76 [Abstract] [Full Version]  
  • McIlhaney, J. S. Jr, (2005). Problems and Solutions Associated With Media Consumption: The Role of the Practitioner. Pediatrics 116: 327-328 [Full Version]  
  • Kahn, J. A., Rosenthal, S. L., Succop, P. A., Ho, G. Y. F., Burk, R. D. (2002). Mediators of the Association Between Age of First Sexual Intercourse and Subsequent Human Papillomavirus Infection. Pediatrics 109: e5-5 [Abstract] [Full Version]  
  • Schoen, E. J. (2003). It's Wise to Circumcise: Time to Change Policy. Pediatrics 111: 1490-1491 [Full Version]  
  • Dempsey, A. F., Zimet, G. D., Davis, R. L., Koutsky, L. (2006). Factors That Are Associated With Parental Acceptance of Human Papillomavirus Vaccines: A Randomized Intervention Study of Written Information About HPV. Pediatrics 117: 1486-1493 [Abstract] [Full Version]  
  • Buchanan;, I. D., Blake, D. R., Duggan, A., Quinn, T., Zenilman, J., Joffe, A. (2000). Evaluation of Vaginal Infections in Adolescent Women: Can It Be Done Without a Speculum?. Pediatrics 105: 156-157 [Full Version]  
  • Beck-Sague;, C. M., Stevens-Simon, C. (2001). Child Sexual Abuse and Human Papillomavirus Infection. Pediatrics 108: 1045-1045 [Full Version]  
  • Sinclair, K. A., Woods, C. R., Kirse, D. J., Sinal, S. H. (2005). Anogenital and Respiratory Tract Human Papillomavirus Infections Among Children: Age, Gender, and Potential Transmission Through Sexual Abuse. Pediatrics 116: 815-825 [Abstract] [Full Version]