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Section 3. Summaries of Infectious Diseases
Human Papillomaviruses
Clinical Manifestations
Etiology
Epidemiology
Diagnostic Tests
Treatment
Isolation of the Hospitalized Patient
Control Measures
CLINICAL MANIFESTATIONS: Most human papillomavirus (HPV) infections
produce no lesions and are inapparent clinically. However, HPVs
can produce benign epithelial proliferation (warts) of the skin
and mucous membranes and are associated with anogenital dysplasias
and cancers. Cutaneous nongenital warts include common skin
warts, plantar warts, flat warts, thread-like (filiform) warts,
and epidermodysplasia verruciformis. Warts also occur on the
mucous membranes, including the anogenital, oral, nasal, and
conjunctival areas and the respiratory tract, where respiratory
papillomatosis occurs.
Common skin warts are dome-shaped with conical projections that give the surface a rough appearance. They usually are painless and multiple, occurring commonly on the hands and around or under the nails. When small dermal vessels become thrombosed, black dots appear in the warts. Plantar warts on the foot may be painful and are characterized by marked hyperkeratosis, sometimes with black dots.
Flat warts ("juvenile warts") commonly are found on the face and extremities of children and adolescents. They usually are small, multiple, and flat topped; seldom exhibit papillomatosis; and rarely cause pain. Filiform warts occur on the face and neck. Cutaneous warts are benign.
Anogenital warts, also called condylomata acuminata, are skin-colored warts with a cauliflower-like surface that range in size from a few millimeters to several centimeters. In males, these warts may be found on the penis, scrotum, or anal and perianal area. In females, these lesions may occur on the vulva or perianal areas and less commonly in the vagina or on the cervix. Anogenital warts often are multiple and attract attention because of their appearance. Warts usually are painless, although they may cause itching, burning, local pain, or bleeding.
Anogenital HPV infection may be associated with clinically . . . [Go to Full Text]
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- Giaquinto, C., Del Mistro, A., De Rossi, A., Bertorelle, R., Giacomet, V., Ruga, E., Minucci, D.
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