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Appendices

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Section 1. Active and Passive Immunization

Active Immunization

Vaccine Safety and Contraindications

Risks and Adverse Events
Institute of Medicine Immunization Safety Review Committee
The Brighton Collaboration

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RISKS AND ADVERSE EVENTS

All licensed vaccines in the United States are safe and effective, but no vaccine is completely safe and effective in every person. Some vaccine recipients will have an adverse event, and some will not be protected fully. The goal of vaccine development is to achieve the highest degree of protection with the lowest rate of adverse events. Adverse events following immunization include both true vaccine events and coincidental events that would have occurred without vaccination. As immunizations successfully eliminate their target vaccine-preventable diseases, vaccine safety issues have received more attention, increasing the need for immunization providers to communicate risks and benefits of immunizations to a population whose first-hand experience with vaccine-preventable diseases increasingly is rare. Many families lack awareness of the continued threat of vaccine-preventable diseases (eg, pertussis, measles, mumps, invasive H influenzae) among unimmunized people.

Risks of immunization may vary from minor and inconvenient to severe and life threatening. Rarely, serious adverse events following immunization occur, resulting in permanent sequelae or life-threatening illness. . . . [Go to Full Text]


Related text in Red Book:

Reporting of Adverse Events

Red Book 2009: 42-51. [Extract] [Full Version]  

Common Misconceptions About Immunizations

Red Book 2009: 51-55. [Extract] [Full Version]  

Rubella

Red Book 2009: 579-584. [Extract] [Full Version]  

Varicella-Zoster Infections

Red Book 2009: 714-727. [Extract] [Full Version]  

Measles

Red Book 2009: 444-455. [Extract] [Full Version]  

Mumps

Red Book 2009: 468-472. [Extract] [Full Version]  

Appendix IV. National Childhood Vaccine Injury Act and Reporting and Vaccine Injury Table

Red Book 2009: 842-844. [Extract] [Full Version]  

Appendix V. Nationally Notifiable Infectious Diseases in the United States

Red Book 2009: 845-846. [Extract] [Full Version]  

Appendix VII. Standards for Child and Adolescent Immunization Practices

Red Book 2009: 854-856. [Extract] [Full Version]