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Section 3. Summaries of Infectious Diseases
Ureaplasma urealyticum Infections
Clinical Manifestations|
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CLINICAL MANIFESTATIONS
The most common syndrome associated with Ureaplasma urealyticum infections is nongonococcal urethritis (NGU). Although 15% to 55% of cases of NGU are caused by Chlamydia trachomatis, U urealyticum has been implicated as an etiologic agent in many of the remaining cases. Without treatment, the disease usually resolves within 1 to 6 months, although asymptomatic infection may persist thereafter. Prostatitis and epididymitis also have been associated with U urealyticum infection in men. In women, salpingitis, endometritis, and chorioamnionitis can occur. There is an association between infection and infectivity and recurrent pregnancy loss. Recently, association of U urealyticum as a cofactor with HPV in the development of cervical cancer has been described.
U urealyticum has been isolated from the lower respiratory tract and from lung biopsy specimens of preterm infants and contributes to intrauterine pneumonia and chronic lung