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Section 3. Summaries of Infectious Diseases
Chancroid
Clinical ManifestationsEtiology
Epidemiology
Diagnostic Tests
Treatment
Isolation of the Hospitalized Patient
Control Measures
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CLINICAL MANIFESTATIONS
Chancroid is an acute ulcerative disease that involves the genitalia. An ulcer begins as a tender erythematous papule, becomes pustular, and erodes over several days, forming a sharply demarcated, somewhat superficial lesion with a serpiginous border. The base of the ulcer is friable and can be covered with a gray or yellow, necrotic, and purulent exudate. Single or multiple ulcers can be present. Unlike a syphilitic chancre, which is painless, the chancroidal ulcer often is painful and nonindurated. The ulcer can be associated with a painful, unilateral inguinal adenitis (bubo), which often is suppurative. Without treatment, ulcer(s) may resolve in several weeks.
In most males, chancroid manifests as a genital ulcer with or without inguinal tenderness and can present less commonly as purulent urethritis; edema of the prepuce is common. In females, most lesions are at the vaginal introitus and symptoms include dysuria, dyspareunia, vaginal discharge, pain on defecation, or anal bleeding. Constitutional symptoms are unusual.
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ETIOLOGY
Chancroid is caused by Haemophilus ducreyi, which is
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