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Section 3. Summaries of Infectious Diseases

Lymphocytic Choriomeningitis

Clinical Manifestations
Etiology
Epidemiology
Diagnostic Tests
Treatment
Isolation of the Hospitalized Patient
Control Measures

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CLINICAL MANIFESTATIONS

Postnatal infection is asymptomatic in approximately one third of cases. Symptomatic infection may result in a mild to severe influenza-like illness, which includes fever, malaise, myalgia, retro-orbital headache, photophobia, anorexia, and nausea. Fever usually lasts 1 to 3 weeks, and rash is rare. A biphasic febrile course is common; after a few days without symptoms, the second phase may occur in up to half of symptomatic patients, consisting of neurologic manifestations that vary from aseptic meningitis to severe encephalitis. From 10% to 15% of all cases of aseptic meningitis are caused by lymphocytic choriomeningitis (LCM) virus, and it can be the most common cause of aseptic meningitis during winter months. . . . [Go to Full Text]


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