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The first 300 words of the full text of this section appear below.

Section 3. Summaries of Infectious Diseases

Human Papillomaviruses

Clinical Manifestations
Etiology
Epidemiology
Diagnostic Tests
Treatment
Isolation of the Hospitalized Patient
Control Measures and Care of Exposed People

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CLINICAL MANIFESTATIONS

Most human papillomavirus (HPV) infections produce no lesions and are inapparent clinically. However, HPVs can produce benign epithelial proliferation (warts) of the skin and mucous membranes and are associated with anogenital dysplasias and cancers. Cutaneous nongenital warts include common skin warts, plantar warts, flat warts, thread-like (filiform) warts, and epidermodysplasia verruciformis. Warts also occur on the mucous membranes, including the anogenital, oral, nasal, and conjunctival areas and the respiratory tract, where respiratory papillomatosis occurs.

Common skin warts are dome-shaped with conical projections that give the surface a rough appearance. They usually are painless and multiple, occurring commonly on the hands and around or under the nails. When small dermal vessels become thrombosed, black dots appear in the warts. Plantar warts on the foot may be painful and are characterized by marked hyperkeratosis, sometimes with black dots.

Flat warts ("juvenile warts") commonly are found on the face and extremities of children and adolescents. They usually are small, multiple, and flat topped; seldom exhibit papillomatosis; and rarely cause pain. Filiform warts occur on the face and neck. Cutaneous warts are benign.

Anogenital warts, also called condylomata acuminata, are skin-colored warts with a cauliflower-like surface that range in size from a few millimeters to several centimeters. In males, these warts may be found on the penis, scrotum, or anal and perianal area. In females, these lesions may occur on the vulva or perianal areas and less commonly in the vagina or on the cervix. Anogenital warts often are multiple and attract attention because of their appearance. Warts usually are painless, although they may cause itching, burning, local pain, or bleeding.

Persistent anogenital HPV . . . [Go to Full Text]


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