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Section 4. Antimicrobial Agents and Related Therapy
Appropriate and Judicious Use of Antimicrobial Agents
Principles of Appropriate Use of Vancomycin 245
Increased use of vancomycin is responsible for the frequent occurrence of vancomycin-resistant enterococcal colonizations and infections as well as the infrequent emergence of vancomycin-intermediately susceptible and vancomycin-resistant strains of S aureus. Risk occurs particularly among patients receiving hematology-oncology, nephrology, neonatology, cardiac surgery, and neurosurgery services. Prevention of further emergence of vancomycin resistance will depend on more limited use of vancomycin for treatment and prophylaxis.
Situations in Which Use of Vancomycin is Appropriate Include the Following
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